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Medications

Buspirone (BuSpar)

Buspirone is a daily anti-anxiety medication, sold as BuSpar, used for generalized anxiety. It isn't sedating and isn't habit-forming, but it takes weeks to work.

Also known as: BuSpar

What the word means

Buspirone is the drug. BuSpar is the old brand name.

It’s an anxiolytic that doesn’t behave like the anxiolytic most people picture. It isn’t a benzodiazepine. It isn’t sedating, it isn’t a controlled substance, and it carries no meaningful risk of physical dependence.

The catch is the one that trips people up constantly: it’s a daily medication and it takes weeks to build an effect. Taken as needed in a moment of anxiety, it does essentially nothing, and someone who tries it that way will reasonably conclude it’s useless. It isn’t useless. It’s just being used wrong.

Where to read the full guide

Shrinktionary defines the word.

Read the full buspirone guide at PsychiatryRx, which covers dosing, what to expect, and how it compares with a benzodiazepine.

When to seek professional care

Take it on the schedule you were given rather than only when anxiety spikes, because that’s the difference between it working and it seeming worthless. If several weeks have passed and nothing has changed, that’s worth reporting rather than quietly abandoning. If you have thoughts of harming yourself, get help right away by calling 911, or call or text 988 in the US to reach the Suicide and Crisis Lifeline.

Related terms

Sources

  1. Buspirone: MedlinePlus Drug Information , MedlinePlus (U.S. National Library of Medicine)
  2. Anxiety Disorders , National Institute of Mental Health
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<blockquote>
  <p><strong>Buspirone (BuSpar):</strong> Buspirone is a daily anti-anxiety medication, sold as BuSpar, used for generalized anxiety. It isn't sedating and isn't habit-forming, but it takes weeks to work.</p>
  <p>&mdash; <a href="https://shrinktionary.com/terms/buspirone/">Shrinktionary</a>, a plain-English mental health dictionary, medically reviewed by a board certified psychiatrist.</p>
</blockquote>

Cite (APA)

Refai, S. (2026). Buspirone (BuSpar). Shrinktionary. https://shrinktionary.com/terms/buspirone/

Cite (MLA)

"Buspirone (BuSpar)." Shrinktionary, https://shrinktionary.com/terms/buspirone/. Accessed July 25, 2026.

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