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Medications

Akathisia

Akathisia is a distressing sense of inner restlessness, often with a strong urge to keep moving. It's a side effect that can come from certain psychiatric medications and warrants prompt attention.

Also known as: Inner restlessness

What akathisia actually is

Akathisia is a feeling of intense inner restlessness, usually paired with a hard-to-resist urge to move. People describe it as not being able to sit still, a buzzing under the skin, or a sense that they have to keep shifting, pacing, or rocking to get relief. The word comes from Greek and roughly means “inability to sit.”

It’s a known side effect of some psychiatric medications, especially certain antipsychotics, though it can show up with some antidepressants and other drugs too. The discomfort is real and can be quite distressing. In severe cases the agitation it causes can affect mood and, in some people, contribute to thoughts of self-harm, which is one reason it’s taken seriously and treated promptly rather than waited out. Severity ranges widely, from a mild sense of restlessness that comes and goes to a relentless drive to move that makes it nearly impossible to rest.

What it looks like

From the outside, akathisia can look like fidgeting, pacing, foot-tapping, rocking, crossing and uncrossing the legs, or an inability to stay seated. From the inside, it feels worse than it looks. The driving sensation is an uncomfortable, sometimes overwhelming need to move, and moving brings only brief relief before the urge returns.

It often starts soon after a medication is begun or a dose is raised, which is why careful titration and monitoring matter early in treatment. Because the inner distress can be mistaken for anxiety or worsening illness, naming it correctly matters. The treatment for restlessness caused by a medication is different from treating an anxiety flare, and getting that wrong can mean raising a dose that is actually causing the problem, which makes the restlessness worse.

What it isn’t

Akathisia isn’t ordinary anxiety, even though it can feel similar. The key clue is the physical, motor-driven urge to move and its timing right after a medication change rather than in response to a worry or situation. It also isn’t a sign that the person can’t manage their emotions, since the driver is the drug’s effect on the brain, not the person’s state of mind.

It also isn’t the same as tardive dyskinesia, which involves involuntary, often repetitive movements that tend to develop later after long-term use. The two are different problems, even though both relate to movement and medication, and telling them apart guides what a prescriber does next. Akathisia tends to appear early and centers on an urge to move, while tardive dyskinesia tends to appear later and involves movements the person isn’t choosing at all.

What to do about it

Akathisia can be serious and very distressing, and it deserves prompt contact with a prescriber. Don’t just push through it or stop the medication on your own, since stopping abruptly carries its own risks. A clinician can confirm what’s happening and adjust the plan, since lowering a dose, slowing the titration, switching medications, or adding a targeted treatment often helps. Reporting it early, especially soon after starting or increasing a medication, gives the best chance of quick relief, and describing exactly when it started makes it easier for a prescriber to pin down the cause.

When this word matters

Akathisia matters because it's a distressing medication side effect, often from antipsychotics, that can be mistaken for worsening anxiety or agitation and warrants prompt attention. Telling it apart matters since the response is to address the medication, not to assume the underlying illness is getting worse.

Commonly confused with

AnxietyAgitationTardive dyskinesiaRestless legs at nightWorsening of the original condition

Frequently asked questions

What does akathisia feel like?

Akathisia is an intense inner restlessness paired with a hard-to-resist urge to move, often described as not being able to sit still or a buzzing under the skin. From the inside it tends to feel worse than it looks from the outside.

Is akathisia the same as anxiety?

No. Although it can feel similar, the key clue with akathisia is a physical, motor-driven urge to move and its timing right after a medication is started or a dose is raised. Treating it differs from treating an anxiety flare.

What should I do if I think I have akathisia?

Akathisia can be serious and distressing, so it deserves prompt contact with a prescriber rather than pushing through it or stopping the medication on your own. Reporting it early gives the best chance of quick relief.

Related terms

Sources

  1. Mental Health Medications , National Institute of Mental Health
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<blockquote>
  <p><strong>Akathisia:</strong> Akathisia is a distressing sense of inner restlessness, often with a strong urge to keep moving. It's a side effect that can come from certain psychiatric medications and warrants prompt attention.</p>
  <p>&mdash; <a href="https://shrinktionary.com/terms/akathisia/">Shrinktionary</a>, a plain-English mental health dictionary, medically reviewed by a board certified psychiatrist.</p>
</blockquote>

Cite (APA)

Refai, S. (2026). Akathisia. Shrinktionary. https://shrinktionary.com/terms/akathisia/

Cite (MLA)

"Akathisia." Shrinktionary, https://shrinktionary.com/terms/akathisia/. Accessed July 25, 2026.

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